https://www.selleckchem.com/products/gdc-0084.html d monounsaturated (m=-0.68; r=0.74; P=0.09) indices, while the polyunsaturated index slope remained similar (m=0.56; r=0.89; P=0.02). Age, sex, height, body mass, and BMI were not associated with the pattern of any of the lipid composition index measures. Study findings in this small sample of individuals with AIS suggest that the bone marrow saturated index may be relatively stable across T11-L4, while the monounsaturated index may decrease by 0.55-0.68% per vertebra and the polyunsaturated index may increase by 0.52-0.56% per vertebra in the caudal direction. Study findings in this small sample of individuals with AIS suggest that the bone marrow saturated index may be relatively stable across T11-L4, while the monounsaturated index may decrease by 0.55-0.68% per vertebra and the polyunsaturated index may increase by 0.52-0.56% per vertebra in the caudal direction. Dynamic high-intensity physical activity is thought to be beneficial for older adults' bone health. Traditional volume-based processing of accelerometer-measured physical activity data, quantified on a minute-per-minute basis, may average out sporadic high impact activity, whereas accelerometer data processing approaches based on identifying impacts can capture also these potentially beneficial short activity bursts. We investigated the associations between habitual physical activity and proximal femur bone traits among sedentary older adults utilizing three different numerical treatments of accelerometer-data to examine, if impact-based processing approaches are more suitable to assess bone loading than volume-based processing of physical activity data among older adults. This cross-sectional study utilized the baseline data from the PASSWORD-study (n=284, mean±SD age 74±4years, 57% women). Total femur bone mineral content (BMC) and bone mineral density (BMD), femoral neck BMC, BMD, section modulus and mivity was positively associated with all bone tra