https://www.selleckchem.com/products/Eloxatin.html Stimuli-responsive gel volume variation is reversible and has shown promising applications, which may be potential for contraction or expansion fabrication, generating shrinking or swelling volume of the original. In this study, a thermo/photo dual-crosslinking hydrogel is prepared with methacrylated hydroxylbutyl chitosan (MHBC) and gelatin methacrylate (GelMA). The M/G hydrogel undergoes sol-gel phase transition under room temperature and shrinking deformation upon elevating temperature. Besides nontoxicity and biodegradability, dual crosslink endowed the composite hydrogel with strengthened and tunable mechanical property, controlled and repeatable contraction property in response to temperature elevation from 25 ℃ to 37 ℃, and enhanced cell adhesion in 3D culture. These peculiarities of M/G hydrogel provide great potential for application in contraction fabrication to acquire high resolution or small scale features that may be limited by fabrications devices. To evaluate the reaction conditions on the physicochemical properties of composites of starch and stearic acid, composites were prepared under reaction conditions that varied the starch concentration (0.5, 1, 3%), stearic acid addition level (5, 10, 25 mg), stearic acid addition rate (2, 4, 8, 16 mL/min), and temperature (70, 80, 90 °C). All conditions significantly impacted the recovery, mean particle size, and zeta potential of samples. Specifically, a higher starch concentration and temperature significantly increased the recovery of stearic acid, but the mean particle size of the composite increased with higher stearic acid addition level and starch concentration. Stearic acid content in the composite exhibited a significant correlation with zeta potential (r = 0.818, p = 0.001). During enzymatic digestion for 20 min, 8% of the stearic acid was released from the composite. Approximately 10 % of the stearic acid was degraded after 36 h of storage at 50°C