https://www.selleckchem.com/products/20-hydroxyecdysone.html Wide-field imaging through dielectric microspheres has emerged in recent years as a simple and effective approach for generating super-resolution images at visible wavelengths. We present, to our knowledge, the first demonstration that dielectric microspheres can be used in a wide-field infrared (IR) microscope to enhance the far field resolution. We have observed a substantial improvement in resolution and magnification when images are collected through polystyrene microspheres. In addition, we demonstrate that spectroscopic imaging with a pulse-shaper based femtosecond mid-IR laser system is possible through the dielectric microspheres, which is a promising first step toward applying this technique to ultrafast IR imaging methods such as pump-probe and 2DIR microscopy.Following up on our recent paper, which reported a machine learning approach to train on and predict thermal rate constants over a large temperature range, we present new results by using clustering and new Gaussian process regression on each cluster. Each cluster is defined by the magnitude of the correction to the Eckart transmission coefficient. Instead of the usual protocol of training and testing, which is a challenge for present small database of exact rate constants, training is done on the full data set for each cluster. Testing is done by inputing hundreds of random values of the descriptors (within reasonable bounds). The new training strategy is applied to predict the rate constants of the O(3P) + HCl reaction on the 3A' and 3A″ potential energy surfaces. This reaction was recently focused on as a "stress test" for the ring polymer molecular dynamics method. Finally, this reaction is added to the databases and training is done with this addition. The freely available database and new Python software that evaluates the correction to the Eckart transmission coefficient for any reaction are briefly described.The delivery of therapeu