https://www.selleckchem.com/products/BMS-754807.html One compound, having a six atom carbocyle central ring in the tricyclic pyrrolothiazole system and bearing a pivalamide group at the thiazole moiety and a 5-chloro-2-methoxyphenyl carboxamide at the pyrrole ring, significantly increased F508del-CFTR activity. This compound could lead to the synthesis of a novel class of CFTR correctors.In recent years, the use of plant fibres in Textile-Reinforced Mortar (TRM) composites emerged as a valuable solution to increase their sustainability. Several studies carried out to mechanically characterize the so-called Natural TRMs, although showing promising results, also emphasised some drawbacks due to a severe deformability of the system and to durability issues. This study aims at improving the mechanical behaviour of Natural TRMs including impregnated flax textile (Flax TRMs) by the addition of short curauá fibres within the matrix. Flax TRM specimens were tested in tension to assess the influence of the fibre-reinforced mortar on the composite response. The crack pattern developed during the test was investigated via Digital Image Correlation analysis and by means of an analytical simplified model proposed by the authors. The addition of curauá fibres resulted in a denser crack pattern and in a significant decrease of the mean crack width (around 20%). The overall tensile response of Flax TRMs including curauá fibres resulted closer to the ideal three-linear behaviour of strain-hardening TRM composites with respect to the conventional Flax TRMs by also presenting an increase of dissipated energy of around 45%. This study paves the way for further analysis aimed at enhancing the mechanical performance of Natural TRMs adopting sustainable improvement techniques. Diet has a relevant role in triggering symptoms in inflammatory bowel disease (IBD) from the patients' perspective, but there is gap the between patients' and doctors' perceptions. Few studies have addressed this to