https://www.selleckchem.com/products/milademetan.html In Japan, the geographical distribution of the first date of flowering (FFD) of Yoshino cherry trees (Cerasus ×yedoensis) in 2020, a year when temperatures were mild during the previous December and March, was different from the average FFD, which progresses northward along a latitudinal gradient. We hypothesized that global warming may have changed the average geographical pattern of the FFD. To test this hypothesis, we examined the relationship between the observed FFD and latitude at 42 sites during the period 1953-2020. We found that the correlation between FFD and latitude had decreased since 1980. This decrease may have been caused by a rise of temperatures in winter that delayed dormancy release and the subsequent FFD in areas where the annual mean temperature is high. Our results suggest that the correlation between FFD and latitude will decrease further as the climate warms in the future.The increasing frequency and intensity of extreme climate events have caused serious impacts on the service functions of terrestrial ecosystems and the production and life of human society in recent years. The warm nights (TN90p) variable of the 26 extreme climate indicators was the main factor controlling the tree radial growth of Schrenk spruce (Picea schrenkiana) in the Tianshan Mountains region based on the responses of tree-ring width in the 5 sample sites. Therefore, TN90p in the growth season from May to September (TN90p5-9) during 1735-2016 was reconstructed on the basis of the time stability of the growth-climate relationships. The interpretation rate of variance of the reconstructed equation was 45.4% (R2adj = 44.4%, F = 45.7). The reconstruction showed four relatively high TN90p5-9 historic intervals (1747-1798, 1856-1872, 1906-1951, and 2002-2016) and four low intervals (1735-1747, 1798-1856, 1872-1900, and 1951-2002). The occurrence frequency of extreme high values was higher than that of extreme low values