The clavicle, modified long bone, presents morphological and bilateral variations. This may be due to genetic factors, hormones, or environmental and occupational influences. Anthropometric studies in clavicle of Nepalese population using radiograph has not been reported to best of our knowledge. This study, aimed to determine the sexual dimorphism and bilateral asymmetry of clavicle in Nepalese Population using Postero-Anterior Chest X Ray.
 
  Chest x-rays with normal and clearly visible both clavicles of 1260 Nepalese adults (591 male, 669 female), aged above 20 years were utilized. Inbuilt software "Computed Radiography Fuji Computer System 7" was used for measurements (in centimeter) of sternal head length, acromial end length, mid shaft diameter and length of clavicle. Demarcating point and identification point were calculated. Patients having history of clavicles fractures in the past were excluded.
 
  All the parameters in male is greater than female which is significant except Length/Mid Shaft Diameter. Similarly, all the parameters of right clavicle is significantly greater than left clavicle in both sexes except Sternal Head Length and Mid Shaft Diameter. Demarcating point calculated from length of the clavicle (right >16.17, left >16.10 for male and right <11.20, left <10.65 for female) and Mid Shaft Diameter (right >1.33, left >1.38 for male and right <0.66 and left <0.67 for female) are important parameters to determine sex. ConclusionsThe clavicle shows significant sexual dimorphism and bilateral asymmetry in Nepalese population. The result of this study is helpful to anthropologist and forensic medicine.
 1.38 for male and right less then 0.66 and left less then 0.67 for female) are important parameters to determine sex. ConclusionsThe clavicle shows significant sexual dimorphism and bilateral asymmetry in Nepalese population.  https://www.selleckchem.com/products/gsk-j4-hcl.html  The result of this study is helpful to anthropologist and forensic medicine.
  The study compared the peak reflux velocity and reflux time in cases of varicose veins and non-varicose veins with a focus on quantifying the reflux parameters.
 
  This is a hospital based observational comparative study. The limbs with CEAP Clinical classification of C2 or more were taken as diseased limbs and contra-lateral limbs with no symptoms or disease were taken as control limbs.
 
  Altogether 792 limbs (452 diseased limbs and 340 control limbs) were evaluated with color duplex. Mean Great Saphenous Vein diameter was 5.68 ± 2.07 mm and 4.00 ± 1.34mmin diseased limbs and control limbs respectively (p=0.0001). Mean sapheno-femoral junction diameter was 8.23 ± 2.64 mm and 6.16 ± 1.93 mm in diseased limbs and control limbs respectively (p=0.0001). Mean peak reflux velocity in diseased limbs was significantly higher than control limbs (77.38 cm/sec vs 7.95 cm/sec; p=0.0001). Similarly mean reflux time was significantly longer in diseased limbs than non-diseased limb (406.58ms and 67.28 ms respectively; p=0.0001). An optimal cut-off point of 27.4 cm/s for peak reflux velocity and 250 ms for the reflux time at Sapheno-Femoral junction had a discriminatory power between the two groups.
 
  The quantification of peak reflux velocity seems to be more consistent than reflux time in determining the superficial venous reflux. An optimal peak reflux velocity cut off point of 27.4 cm/sec has the discriminatory power between diseased and non-diseased limb.
 The quantification of peak reflux velocity seems to be more consistent than reflux time in determining the superficial venous reflux. An optimal peak reflux velocity cut off point of 27.4 cm/sec has the discriminatory power between diseased and non-diseased limb.
  Medical humanities is taught in medical schools in the western countries, partly to address the lack of compassion within healthcare. It seeks to develop understanding of human experiences relating to disease, disability and death, through humanities, arts and social sciences. In 2018, Patan Academy of Health Sciences Nepal introduced an eight-week medical humanities course for new medical students. This study aims to evaluate the course from the student participants' view, exploring their perceptions and experiences.
 
  A mixed method study was used to assess the perceptions of 65 students who completed a semi-structured survey, comprising eight items, with five point- Likert scale and three open response questions. Quantitative data was analysed with results expressed as mean, standard deviation and percentage. Qualitative data was coded and analysed thematically.
 
  The students' perception of the course was strongly positive where 98.5% agreed or strongly agreed it was enjoyable and interesting (items 1,2) and should be continued (item 9). 97% agreed or strongly agreed it made them think differently (item 5) and 96.9% that it was relevant to future careers (item 6). 96.9% agreed or strongly agreed the course helped them understand doctor's caring roles (item 10) and 92.3% believed it will make them better doctors (item 11). Three themes emerged from open response questions related to perceptions- enjoyable and interesting, positive personal impact and valuable and important.
 
  The students had positive perceptions of the medical humanities course, recognizing its' impact, importance and its value in medical education. Its expansion in the undergraduate curriculum should be considered.
 The students had positive perceptions of the medical humanities course, recognizing its' impact, importance and its value in medical education. Its expansion in the undergraduate curriculum should be considered.
  Burn infection is a major cause of morbidity and mortality in spite of significant improvements in burn care and treatment. Pseudomonas aeruginosa, Acinetobacter spp., Staphylococcus aureus etc. are the commonest isolates in which rapid development of resistance to multiple drugs limits the therapeutic options for infections by Acinetobacter species. Hence, this study was done to find the occurrence of Acinetobacter and to determine the minimum inhibitory concentration of tigecycline against Acinetobacter isolates.
 
  This cross-sectional study was conducted in Phect-Nepal Hospital, Kirtipur, Nepal from September to December 2018. Total 205 samples were included for the isolation and identification of Acinetobacter and further minimum inhibitory concentration of isolates were done following the standard laboratory protocol. Collected data were analyzed by SPSS version 23.0.
 
  Among 155 culture positive samples, 27 isolates were Acinetobacter spp. Antimicrobial Susceptibility Test revealed that 24 isolates were resistant to ceftriaxone and ceftazidime, but all isolates were susceptible to polymyxin B.