There is a sudden upsurge in the literature over the last fortnight on strategies to be followed by imaging services during this SARS-CoV-2 global pandemic. This compilation of strategies, experiences, and precautions is intended to support nuclear medicine departments, as they make decisions regarding patient care. These guidelines are a good resource to tackle the current crisis, however, situations such as these may occur again, and long-term readiness measures need to be discussed and implemented.Dens invaginatus (DI) is one of the rare malformations of teeth which results from an infolding of the dental papilla during the development of teeth. This defect gives rise to a possible communication between the pulp and oral environment, thereby increasing the susceptibility to caries, pulpitis, and pulp necrosis. Thus, early detection and conservative management of this invaginatus is of utmost importance. The present case series describes a conservative endodontic treatment technique for the management of teeth with Type II DI using a guided endodontic approach with three-dimensional printed surgical stents. This technique provides a precise and minimally invasive approach in the conservative management of DI, without compromising the vitality of main pulpal tissue.External root resorption of permanent teeth is a multifactorial process. This article presents an unusual case of localized idiopathic extensive external root resorption involving the whole mesial root of the right mandibular first molar in a 42-year-old female patient. No significant systemic, dental, or familial findings could be identified as a possible cause. The cause of the resorption remained unclear. The tooth was managed by nonsurgical endodontic treatment using mineral trioxide aggregate to seal resorbed canals. A 5-year follow-up revealed satisfactory results clinically and radiographically with mobility within physiological limits. This study aims to evaluate and compare the sealing ability of Biodentine™ and mineral trioxide aggregate (MTA) plus on root end cavities treated with 17% ethylene diamine tetraacetic acid (EDTA), 0.2% Chitosan and 1% Phytic acid using Confocal Laser Scanning Microscope (CLSM)-An study. Sixty extracted single rooted teeth were instrumented and obturated with gutta-percha. The apical 3 mm of each tooth was resected and 3 mm root-end preparation was made using ultrasonic tip. 17% EDTA ( = 20), 0.2% Chitosan ( = 20) and 1% Phytic acid ( = 20) was used as a smear layer removing agent and each above group was further subdivided and restored with a root end filling material, Biodentine ( = 10) and MTA Plus ( = 10). The samples were coated with varnish except at the root end and after drying, they were immersed in Rhodamine B dye for 24 h. The teeth were then rinsed, sectioned longitudinally, and observed under CLSM. In the present study, MTA Plus® treated with 1% Phytic acid showed the least microleakage followed by Biodentine™ treated with 1% Phytic acid which was statistically not significant. MTA Plus treated with 17% EDTA showed the highest microleakage when compared to other tested groups. There was a significant difference in microleakage between MTA Plus® and Biodentine™ when treated with 17% EDTA and 0.2% Chitosan. However, more microleakage was seen with Biodentine™ group than MTA plus® group. Root end cavities restored with MTA plus and treated with Phyitc acid showed superior sealing ability. Furthermore, smear layer removing agents will aid in better adaptability of root end filling material. Root end cavities restored with MTA plus and treated with Phyitc acid showed superior sealing ability. Furthermore, smear layer removing agents will aid in better adaptability of root end filling material. Zinc oxide eugenol (ZOE) is one of the most commonly used root canal sealer. However, it has few drawbacks such as cytotoxicity, solubility, and irritation to periapical tissues. The scope of this study was to investigate the setting time, solubility, cytotoxic effects, and anti-inflammatory action of ZOE sealer with the modification of its liquid component by the addition of petasin extract in the ratios 11, 51, and 101. Setting time was evaluated using the Vicat's apparatus. For testing solubility, the American Dental Association's specification #8 was adopted with certain modifications. Protein denaturation assay and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide assay with L929 mouse fibroblast cell lines were used to evaluate the anti-inflammatory property and cytotoxicity, respectively. ZOE sealer with petasin extract in the ratio of 51 showed the least initial and the final setting times. There was no statistically significant difference in the amount of solubility for all the groups at the various time intervals. https://www.selleckchem.com/products/sp2509.html The cytotoxicity of the control group was significantly greater than all the experimental groups, whereas the anti-inflammatory effect of the former was statistically lower. The combination of ZOE with petasin extract in the ratio of 51 showed lower setting time, cytotoxicity, and better anti-inflammatory property. The combination of ZOE with petasin extract in the ratio of 51 showed lower setting time, cytotoxicity, and better anti-inflammatory property. The objective is to evaluate the effect of collagen stabilizing agents-chitosan and proanthocyanidin (PA) on the shear bond strength to dentin and microleakage of resin composite at enamel and cemental walls. Thirty premolars were decoronated 2 mm above cemento-enamel junction and restored with composite resin. Teeth were then randomly divided into three groups Group I - Control, Group II - Pre-treatment with chitosan, and Group III - Pre-treatment with PA. Samples were then subjected to thermocycling for 500 cycles at 5°C and 55°C with the dwell time of 30 s and transfer time of 5-10 s. Then, the samples were subjected to shear bond strength evaluation on Universal testing machine. Shear load was applied until failure occurred. The load to failure was recorded individually and statistical analysis was done. Microleakage was determined by methylene blue dye penetration method and subjected to stereomicroscopic evaluation. Statistical analysis was carried out using Mann-Whitney test and Chi-square test. Group II specimens produced the highest median shear bond strength and group I showed the least.