https://www.selleckchem.com/products/l-histidine-monohydrochloride-monohydrate.html The depletion of NK cells and CD8 T cells in mice mitigated the anti-cancer effect of this combination, thereby highlighting the critical role of NK cells and CD8 T cells in mediating anti-cancer immunity. These findings demonstrated that APS could be used as a topical mucosal adjuvant to enhance the immune check point inhibitor anti-cancer effect.Contamination of water with the copper(II) ions leads to serious diseases such as liver damage and cancer. This deadly effect prompted us to target the synthesis of a novel functionalized chitosan (Cs-BT) to be used as an adsorbent for removing the copper(II) ions from the aqueous solution. The functionalization was done by introducing benzothiazole moiety into the chitosan (Cs) chain and confirmed by the full disappearance of the NH2 band in the FT-IR spectrum of the adsorbent. The TGA-DTG analysis revealed that the functionalization reduced the thermal stability of the adsorbent (Cs-BT) as compared with pure chitosan. The adsorption was evidenced by SEM and EDX analysis. The adsorption study demonstrated that the optimal adsorption conditions were 120 min contact time, pH = 6, and initial Cu(II) concentration 200 mg/L. At these conditions, the Cs-BT achieved a maximum copper adsorption capacity of 1439.7 mg/g. Consequently, Cs-BT could be a promising and efficient Cu adsorbent in water treatment. Study the adsorption kinetics and isotherms manifested that the pseudo-first-order was better than pseudo-second-order and Temkin isotherm was better than Langmuir, Freundlich, and Dubinin-Radushkevich for explaining the adsorption process. The calculated thermodynamic parameters implied the spontaneity and the endothermic nature of the adsorption process.The junctional adhesion molecule-A (JAM-A) is an adhesion molecule present in the surface of several cell types, such as endothelial cells and leukocytes as well as Dendritic Cells (DC). Given t