The analysis of current data concerning the use of oral nutrition supplements (ONS) in cancer patients has been performed. The aim of the research is improving the effectiveness of medical nutrition in cancer patients by clarifying terms, definitions, developing an applied classification of ONS formulas and outlining the basic approaches for their use. MATERIAL AND METHODS Using the keywords «cancer», «oral nutritional supplements», and «siping», the literature was searched in such databases as eLIBRARY (elibrary.ru) and MEDLINE (ncbi.nlm.nih.gov) in Russian and English. RESULTS AND DISCUSSION The definition of this type of nutritional support has been given. The applied classification of ONS formulas has been made. Depending on the energy and protein content, presence of some specific nutrients, osmolarity, nitrogen/non-protein kilocalories ratio and viscosity, they were divided into 3 groups. For the initial assessment of nutritional status of the cancer patient, the European society for medical oncology scale (ESMO, 2008) is the most appropriate. Emphasis is placed on the importance of maintaining physical activity. CONCLUSION An approximate algorithm of ONS prescribing in oncology has been formulated. Copyright© GEOTAR-Media Publishing Group.Reducing the manifestations of food allergy by the inclusion of specialized foods in the nutrition of children and adults suffering from this disease is an important problem. The aim was to obtain and characterize in vitro food protein hydrolysates to evaluate their use in specialized foods with reduced potential allergenicity. MATERIAL AND METHODS Whey protein concentrate (WPC) and chicken egg protein (CEP) and enzymes such as pancreatin and alkalase have been used. Proteolysis of proteins was carried out in an FA-10 fermenter for 3 hours at an enzyme substrate ratio of 150 in dry matter, at optimal pH and temperature for pancreatin and alkalase. Enzymes were inactivated at +75 °C and fermentolizate was ultrafiltered. The solutions were concentrated by reverse osmosis and freeze-dried. The molecular weight distribution of the peptide fractions was evaluated by HPLC. Residual antigenicity was determined by the method of indirect enzyme-linked immunosorbent assay and expressed as the fold of antigenicity reduse in the content of high molecular weight peptides and a decrease in the antigenicity of peptide mixtures based on WPC and CEP to the values that permit their use in hypoallergenic products is achieved by combining proteolysis and double ultrafiltration through a UF10 membrane. Copyright© GEOTAR-Media Publishing Group.Small intestinal bacterial overgrowth (SIBO) is a widespread disease characterized by a significant decrease of the quality of life. Antibiotic treatment of SIBO is usually effective, however, the recurrence rate is high. Microbiota is dependent on dietary pattern of the patient and specific nutrients, therefore the diversity of dietary patterns may be one of the major factor promoting SIBO or its relapses after treatment. The aim of the study was to compare nutritional diversity in patients with SIBО-H2 and in healthy controls. MATERIAL AND METHODS Оne thousand twenty three patients with suspected SIBО were examined. Hydrogen-methane breath test with lactulose was performed in 973 patients, the results of which identified groups with SIBO-H2 (n=522), with SIBO-CH4 (n=340) and without signs of SIBO (n=108). Data on food intake was collected with 24 h recall from all participants. Dietary diversity was assessed using method of calculation of unique values (count base diversity) for 11 groups of food cereals, mvegetables and fruits and berries. The obtained data may be used to develop diet for SIBO patients additionally to the treatment and prevention of its relapses. Copyright© GEOTAR-Media Publishing Group.A diet rich in non-digestible plant polysaccharides (dietary fibers) leads to effective appetite suppression and reduces food intake. The mechanical properties of food contribute to the satiating effect of food. It is known that solid food satiates to a greater extent than liquid, as the duration of food processing in the oral cavity increases. The aim of the study was to assess the effect of mechanical properties of agar-pectin gels on the feeding behaviour of mice Material and methods. The gels were prepared by dissolving the corresponding weights of agar, pectin and sucrose in 100 ml of water gel 1 contained 6 g of agar, 3 g of pectin, gel 2 - 20 g of agar, 1 g of pectin and 0.03 M CaCl2, gel 3 - 20 g of agar, 1 g of pectin (without the addition of calcium ions). All gels contained an equal amount of sucrose (15 g per 100 ml of water). The mechanical properties of the gels (strength, Young's modulus and elasticity) were determined on a texture analyzer.  https://www.selleckchem.com/products/BIBF1120.html  Mice with an initial body weight of 32.9±0.5 g (n=8 i 19% (p less then 0.05) in fasted mice. Gels 1 and 2 did not alter the eating behaviour of fasted mice. Fed mice that received gels ate as much food as in the control. Gels failed to affect the eating behaviour of fed mice. Conclusion. Overall, solid gel 3 reduced food intake and time spent on feeding after 14 h of complete food restriction. The effect of the gel on the feeding behaviour of animals and the amount of food eaten is determined by the hardness of the gel and does not depend on the ratio of the components of the gel and its resistance to in vitro simulated gastric and intestinal fluids. Copyright© GEOTAR-Media Publishing Group.Food and medicinal plants as well as its' fruits, used in traditional medicine, are now widely used as sources of bioactive phytochemical compounds to impart functional properties to products. Due to the significant variation in phytonutrient content depending on geoclimatic conditions, a comparative study of goji berries collected in different regions seems to be relevant. The aim - comparative study of L. barbarum and L. chinense berries and its biological effects when inclusion in the diet of rats with experimental hyperlipidemia. MATERIAL AND METHODS In the berries of L. barbarum (China) and L. chinense (Kazakhstan), the composition of monosaccharides, the content of vitamins (D, E, C), minerals (Mg, Ca, Se), phenolic compounds and steroid substances as well as catalase and superoxide dismutase activity and total antioxidant activity was determined. Biological experiment lasted 186 days, it was carried out on Wistar rats, divided into intact (n=10) and experimental animals (n=48), in which alimentary hyperlipidemia was reproduced for 100 days (diet containing animal fats 5.