https://www.selleckchem.com/products/1-nm-pp1.html le with T2DM. This trial was registered at PROSPERO (https//www.crd.york.ac.uk/PROSPERO/#recordDetails) as CRD42019120531. When compared with lower intake, increased MAC intake improved glycemic control, blood lipid, body weight, and inflammatory markers for people with T2DM. This trial was registered at PROSPERO (https//www.crd.york.ac.uk/PROSPERO/#recordDetails) as CRD42019120531. Atrial fibrillation (AF) is the most common cardiac arrhythmia and can lead to significant comorbidities and mortality. Persistence with oral anticoagulation (OAC) is crucial to prevent stroke but rates of discontinuation are high. This systematic review explored underlying reasons for OAC discontinuation. A systematic review was undertaken to identify studies that reported factors influencing discontinuation of OAC in AF, in 11 databases, grey literature and backwards citations from eligible studies published between 2000 and 2019. Two reviewers independently screened titles, abstracts and papers against inclusion criteria and extracted data. Study quality was appraised using Gough's weight of evidence framework. Data were synthesised narratively. Of 6,619 sources identified, 10 full studies and 2 abstracts met the inclusion criteria. Overall, these provided moderate appropriateness to answer the review question. Four reported clinical registry data, six were retrospective reviews of patients' medical poorly understood. To describe, in a real-life setting, the direct causes of death in a cohort of consecutive patients with giant cell arteritis (GCA). We retrospectively analyzed the deaths that occurred in a cohort of 470 consecutive GCA patients from a center of expertise between January 2000 and December 2019. Among the 120 patients who died, we retrieved data from the medical files of 101 patients. Cardiovascular events were the dominant cause of death (n = 41; 41%) followed by infections (n = 22, 22%), geriatric situations (i.e. fall