85±6.09 years.Group1 showed significantly more improvement in all variables of hamstring flexibility and perceived pain at both post-intervention checkups compared to group 2 (p<0.05). Dynamic oscillatory stretch technique was found to be more effective in improving hamstring flexibility and perceived pain compared to static stretching technique. Dynamic oscillatory stretch technique was found to be more effective in improving hamstring flexibility and perceived pain compared to static stretching technique. To assess early and late outcome in severe chronic kidney disease patients undergoing revascularisation. The retrospective ambi-directional cohort study was conducted at Tabba Heart Institute, Karachi, and comprised data from May, 2012, to July,2016, related to severe chronic kidney disease patients with creatinine clearance <30ml/min or end-stage renal disease on haemodialysis who had undergone coronary artery bypass graft / percutaneous coronary intervention. Early outcome was in-hospital major adverse cardiac event, like mortality, stroke and new haemodialysis. Late outcome was major adverse cardiac event, like mortality, stroke, re infarction and re-revascularisation. Data was analysed using Stata 12.1. Of the 228 patients with mean age of 64.2±10.8 years, 109(47.8%) with a maen age of 65.4±11.6 had undergone percutaneous coronary intervention, and 119(52.2%) with a mean age of 64.2±10.8 years had undergone coronary artery bypass graft. https://www.selleckchem.com/products/sb225002.html Overall mortality was 36(15.8%) patients; 15(13.7%) percutanents had higher early mortality, but improved late survival. Ovarian hyperstimulation syndrome (OHSS) is the most common iatrogenic complication due to ovulation stimulation during assisted reproductive technology. Pathophysiology of this syndrome is not completely clarified, and there is no some specific treatment. Human chorionic gonadotropin is considered as the most significant factor in etiopathogenesis of OHSS. The results of some clinical studies related to influence of OHSS on pregnancy are variable. The aim of this study was to investigate hypertensive disease of pregnancies in patients admitted to hospital due to severe forms of OHSS with reference to maternal characteristics. A case control study was conducted at the Obstetrics and Gynaecology Clinic "Narodni Front" and involved 50 patients admitted to hospital due to severe form of OHSS during a period from January 2008 to March 2015. A control group was created based on age and it involved 59 patients with pregnancy achieved with IVF/ICSI during the same period, but in which OHSS did not occur. For comparing mean values of continuous variables, Independent samples t test was applied. Patients with pregnancy complicated by OHSS, had considerably higher rate of hypertension (14% vs. 3.2 %, p=0.046). Pregnancies achieved by IVF/ICSI, being complicated with severe OHSS could be related to gestational hypertension. Pregnancies achieved by IVF/ICSI, being complicated with severe OHSS could be related to gestational hypertension. To evaluate liver and inflammatory biomarkers in occupationally exposed radiology workers. The descriptive study was conducted at Mufti Mehmood Memorial Teaching Hospital and Gomal Centre of Biochemistry and Biotechnology, Gomal University, Dera Ismail Khan, Pakistan, from September 2017 to May 2018, and comprised X-ray technicians working 48-72 hours per week, and a group of age- and gender-matched unexposed healthy controls. The exposed group was divided into three sub-groups based on their radiation work duration. Liver health status involved estimation of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase GGT and bilirubin through automated chemistry analyser, while serum tumour necrosis factor-alpha and interleukin- 6 levels through enzyme-linked immunosorbent assay technique. Relative gene expression analysis of tumour necrosis factor-alpha and alkaline phosphatase was performed through reverse transcription-polymerase chain reaction. Data was analenes. Serum proteomic analysis of X-ray technicians indicated acute inflammatory conditions, while genomic analysis exhibited down-regulation of alkaline phosphatase and tumour necrosis factor-alpha genes. To determine level of trace metals in patients with depression in order to explore any association between the two. The case-control study was conducted at the Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology and Armed Forces Institute of Mental Health, Rawalpindi, Pakistan, from January to December 2017, and comprised diagnosed cases of depression with equal number of age- and gender-matched controls. Depression was diagnosed by a consultant psychiatrist as per the International Classification of Diseases version 10 / Diagnostic and Statistical Manual of Mental Disorders -IV criteria and a self-reported depression screening through Siddiqui-Shah Depression Scale. Blood samples were collected from each subject for the measurement of metals like zinc, chromium and copper. Data was analysed using SPSS 24. Of the 370 subjects, there were 185(50%) in each of the two groups. There were 82(44.3%) males and 103(55.7%) females among the cases with an overall mean age of 37.75±11.49 years, and 65(35.1%) males and 120(64.9%) females with an overall mean age of 39.38±12.56 years among the controls. Mean levels of zinc and copper were significantly different between the groups (p<0.05), while the difference was non-significant for chromium (p>0.05). Equivocal prevalence of depression was present between males and females (p=0.04) without any significant age group association (p=1.92). Blood level of serum zinc and copper were found to be associated with depression. Blood level of serum zinc and copper were found to be associated with depression. To compare the mean decrease in mouth opening by autologous blood injection in superior joint space with and without pericapsular tissue in the treatment of chronic recurrent temporomandibular joint dislocation. The prospective study was conducted at the department of Oral and Maxillofacial Surgery, King Edward Medical University, Mayo Hospital, Lahore, Pakistan, from July, 2015, to January, 2016, and comprised patients, divided into two equal groups, having chronic temporomandibular joint dislocation. Group A patients were injected with autologous blood 2ml by 18-gauge single needle technique in superior joint space, while in group B patients, the needle was moved outward for 1cm and an additional 1ml of blood was injected in the pericapsular tissue under local anaesthesia in single setting after scrubbing local area with antiseptic solution. Data was analysed using SPSS 17. Of the 80 patients, there were 40(50%) in each of the two groups. In group A, there were 18(45%) males and 22(55%) females with an overall mean age of 30.