hat need further study.Research on the impacts of climate change on water quality helps to better formulate water quality strategies under the challenge of an uncertain future, which is critical for human survival and development. As a result, in recent years, there has been growing attention given to research in the field, and the attention has led to an increasing number of publications, which is why a systematic literature review on this topic has been proposed in the current paper. This study reviewed 2998 related articles extracted from the Science Citation Index-Expanded (SCI-E) database from 1998 to 2018 to analyse and visualize historical trend evolution, current research hotspots, and promising ideas for future research by combining a traditional literature review, bibliometric analysis, and scientific knowledge mapping. The results revealed that the impacts of climate change on water quality mainly included the aggravation of eutrophication, changes in the flow, hydrological and thermal conditions, and the destruction of ecosystems and biodiversity. Further exploration of the influence mechanism of climate change on cyanobacteria is an emerging research topic. Additionally, the water quality conditions of shallow lakes and drinking water are promising future research objects. In the context of climate change, the general rules of water quality management and the scientific planning of land use are of great significance and need to be further studied. This study provides a practical and valuable reference for researchers to help with the selection of future research topics, which may contribute to further development in this field.Endocrine-disrupting compounds are attracting attention worldwide because of their effects on living things in the environment. Ten endocrine disrupting compounds 4-nonylphenol, 2,4-dichlorophenol, estrone, 17β-estradiol, bisphenol A, 4-tert-octylphenol, triclosan, atrazine, imidazole and 1,2,4-triazole were investigated in four rivers and wastewater treatment plants in this study. Rivers were sampled at upstream, midstream and downstream reaches, while the influent and effluent samples of wastewater were collected from treatment plants near the receiving rivers. Sample waters were freeze-dried followed by extraction of the organic content and purification by solid-phase extraction. Concentrations of the compounds in the samples were determined with ultra-high performance liquid chromatography-tandem mass spectrometry. The instrument was operated in the positive electrospray ionization (ESI) mode. The results showed that these compounds are present in the samples with nonylphenol > dichlorophenol > bisphenol A > triclosan > octylphenol > imidazole > atrazine > triazole > estrone > estradiol. Nonylphenol has its highest concentration of 6.72 μg/L in King Williams Town wastewater influent and 2.55 μg/L in midstream Bloukrans River. Dichlorophenol has its highest concentration in Alice wastewater influent with 2.20 μg/L, while it was 0.737 μg/L in midstream Bloukrans River. Uitenhage wastewater effluent has bisphenol A concentration of 1.684 μg/L while it was 0.477 μg/L in the downstream samples of the Bloukrans River. Generally, the upstream samples of the rivers had lesser concentrations of the compounds. The wastewater treatment plants were not able to achieve total removal of the compounds in the wastewater while runoffs and wastes dump from the cities contributed to the concentrations of the compounds in the rivers.After political sovereignty, Uzbekistan's industry is growing fast. However, no investigation was performed so far, to evaluate whether an environmental risk, associated with the industry, is also increasing. Our aim was to investigate whether the distance from factories, as a surrogate measurement for environmental exposure to community, has any influence on some health outcomes in communities of Uzbekistan. For this first investigation, we analyzed prevalence of congenital diseases, infant mortality, and incidence rates of lung cancer, as examples for diseases associated with environmental factors. As crude measurement for the association, we used correlation and regression analysis with the distance to the next factory or plant as explanatory variable.  https://www.selleckchem.com/products/k03861.html  A regression analysis demonstrated an association between the three outcome variables, with the strongest negative correlation (r = - 0.48) and the highest determination power (r2 = 0.23) for congenital diseases' prevalence. For infant mortality and lung cancer incidence, descriptions and analyses demonstrated lower negative correlation of them with the distance and a lower predictive power of linear models. So, closer distance of the community to specific industrial plants can be considered an indirect factor of higher prevalence of congenital diseases in those communities. Prospective research is needed to further investigate whether the association between birth defects in a neighborhood of industrial plants is causal or due to confounding factors. A policy should consider a degree of known factors distribution in an environment and perform effective prevention of congenital diseases, in close communities.The Open Dialogue approach was developed in Finland in the 1980s as a form of psychotherapy and a way to organize mental health systems. It has been adapted and implemented in several countries in recent years. This qualitative study sought to explore staff and developers' experiences with one adaptation of the Open Dialogue approach in the state of Vermont called the Collaborative Network Approach. In total twenty two staff members from two agencies participated in focus groups and three developers of the approach were interviewed. Three dominant topics emerged in the analysis process impact of training; buy-in across levels; and shift in organizational culture. Findings revealed that 1) participants experienced the Collaborative Network Approach as positively impacting their clinical work, relationship with clients and families, and with colleagues; 2) buy-in across levels - colleagues, management and department of mental health - was perceived as crucial to the development and implementation of the approach; 3) the main challenges to full implementation were inadequate billing structures, costly and lengthy training, and resistance to shift organizational culture to integrate the Collaborative Network Approach into agencies.