https://www.selleckchem.com/products/Vorinostat-saha.html This study aimed to survey the level of knowledge and practice on medication adherence among Type II diabetes mellitus (DM) patients. A cross-sectional study was conducted with a total of 220 DM patients by using a convenience sampling method. It was found that 64.5% of studied participants have a high level of knowledge with good practice toward medication adherence. There was a significant association between sociodemographic characteristics with the level of knowledge and practice toward medication adherence. This study finding provides information to health care providers to improve their patient's care by playing their important role in promoting the importance of knowledge on medication adherence for a better quality of life to the DM patients. Not only a physician but also the nurse could enhance health education for their patient on medication adherence during the follow-up appointment.This study explored the facilitators and barriers self-management of patients' early stages chronic kidney disease (CKD). This study used a descriptive phenomenological qualitative design, eight participants were recruited using a purposive technique sampling. The data collection instruments employed included in-depth interviews using semi-structured interview guidelines, field notes, and tape recorders. The Colaizzi method was used for data analysis. The results were two themes (1) facilitator of self-management health status, self-motivation, and independence in activities; (2) barriers of self-management personal characteristics of the patients, has a miss-perception about the disease, dependency and not compliance. This study identified facilitators and barriers of self-management patients with early stages of CKD. Therefore, nurses have an important role in conducting a comprehensive health assessment.This literature review was conducted systematically to identify the gap in knowledge and practice related to the pr