Posttraumatic chronodisruption may, thus, affect fundamental properties of neuroendocrine, immune and autonomic systems, leading to a breakdown of biobehavioral adaptive mechanisms with increased stress sensitivity and vulnerability. Given that many traumatic events occur in the late evening or night hours, we also describe how the time of day of trauma exposure can differentially affect the stress system and, finally, discuss potential chronotherapeutic interventions. Conclusion Understanding the stress-related mechanisms susceptible to chronodisruption and their role in PTSD could deliver new insights into stress pathophysiology, provide better psychochronobiological treatment alternatives and enhance preventive strategies in stress-exposed populations.Background Children and adolescents in foster care often experience many co-occurring subtypes of maltreatment. However, little is known about different combinations of maltreatment subtypes, referred to as maltreatment classes. Furthermore, the association between those maltreatment classes and ICD-11 posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD) has not been investigated in children and adolescents. In previous studies, classes characterized by cumulative maltreatment were associated with severe psychopathological symptoms. So far, no study investigated ICD-11 PTSD and CPTSD. Objective The first aim of this study was the detection of distinct maltreatment classes by examining frequently co-occurring maltreatment subtypes. The second aim was the examination of the association between those maltreatment classes and ICD-11 PTSD and CPTSD. Method Participants were 147 children and adolescents currently living in foster care institutions in Lower Austria. Maltreatment history, ICD-11 PTSD and CPTstinct maltreatment classes with ICD-11 PTSD and CPTSD might provide implications for targeted prevention, assessment and treatment.Background Emergency room personnel are indirectly exposed to many traumas. Few studies have examined secondary traumatic stress in emergency room nurses and only a single study examined emergency room physicians. The extent of vicarious post-traumatic growth, i.e., the growth associated with such trauma, has also hitherto not been examined in emergency room personnel. Objective Our first goal was to examine secondary traumatization in both emergency room nurses and physicians. Our second goal was to examine vicarious post-traumatic growth in emergency room personnel.  https://www.selleckchem.com/products/zotatifin.html  Finally, we also address the association (linear and curvilinear) between secondary traumatization and vicarious traumatic growth. Methods A questionnaire comprising demographic variables, secondary traumatic stress and vicarious post-traumatic growth was administered electronically to a sample of emergency room personnel from the Wolfson Hospital, Holon, Israel. Results There were no differences between nurses and physicians in overall secondary trauma or vicarious post-traumatic growth levels. For physicians, there was both a linear and a curvilinear association between secondary trauma and vicarious post-traumatic growth; for nurses, there was no overall association. Further sub-group analyses revealed that emergency room nurses with low workload, in conjunction with low work experience, did show a linear association. Conclusion Results indicate that while vicarious post-traumatic growth is linked to secondary traumatic stress for emergency room physicians, it is not so for nurses. Theoretical implications concerning the role of trauma symptoms in vicarious post-traumatic growth are discussed. Clinical implications are raised regarding the identification of excessive secondary traumatic stress levels and the need for interventions to both decrease stress levels, and to increase vicarious post-traumatic growth levels.Background Polyvictimization is associated with posttraumatic stress disorder (PTSD), severe impairment, and re-victimization, including due to intimate partner violence (IPV), but polyvictmization's role in the perpetration of IPV is less clear. Objective To examine the indirect effect of PTSD and complex PTSD in the relationship between polyvictimization and IPV perpetration. Method Polyvictims were identified by cluster analysis of self-reported lifetime victimization history data in a random national sample (N = 234) of men at 66 clinical treatment centers for domestic violence perpetrators in Israel. Results Four sub-groups were identified low exposure to abuse and physical neglect (C1, N = 105), and three polyvictim sub-groups characterized by multiple forms of past exposure to neglect and verbal abuse (C2, N = 38), to verbal and physical abuse without neglect (C3, N = 46), or to neglect and both verbal and physical abuse (C4, N = 28). Participants also were characterized as having low exposure to traumatic events across the lifespan (cluster L5, N=156), or high exposure to traumatic events across the lifespan (cluster L6, N=78). Complex PTSD symptoms had an indirect effect in the relationship between membership in the C3 and C4 polyvictimization clusters (β=.45, p less then .05, β=.60, p less then .05; respectively) and severity of psychological IPV victimization, as well as between C3 polyvictimization cluster membership and severity of psychological IPV perpetration (β=.32, p less then .05). In contrast, PTSD symptoms had no indirect effect in any relationship between cluster membership and IPV outcomes. High lifetime trauma exposure also was directly associated with sexual IPV victimization. Conclusions Complex PTSD may be a mechanism linking polyvictimization to the severity of both IPV victimization and perpetration. Clinical implications are discussed.In the recent years, Somalia witnessed a heightened frequency of droughts and conflicts. This article explores the experiences of Somalis during the 2011 and 2016 crises, examining the link between vulnerability and resilience, and the role played by international humanitarian responders in resilience building. The aim of this study is to provide information on how different population groups responded to and managed to survive recurrent shocks; the prevailing drivers of marginalisation and exclusion, and mechanisms through which these are maintained; and the role of external stakeholders. A review of literature was combined with field consultations in four study sites Kismayo Urban, Kismayo Rural, Baidoa and Beledweyne, and complemented by consultations with the Somali diaspora community in Kampala, Uganda. Participatory research methods were used, including participant observation, focus group discussions, household dialogues, livelihood analysis, well-being analysis and gender analysis. The findings of the study revealed an inextricable link between vulnerability, conflict and disasters, with the major challenge facing the most vulnerable Somalis being uncertain about the future.