Introduction After hematopoietic stem cell transplantation (HSCT), natural killer (NK) cells reconstitution is the main barrier against viral infections. Objective To determine that the knowledge on the kinetics of NK cell reconstitution after HSCT contributes to transplant efficient monitoring, which increases the possibility of its success. Method Twenty-one patients undergoing HSCT were included, as well as a control group of clinically healthy individuals. At different time points after transplantation (range of 21 to 670 days), CD3- CD16+ CD56+ NK cells were quantified by flow cytometry in peripheral blood samples. Results NK cell recovery occurs at three to six months and 10 to 12 months post-transplantation; their number was significantly lower (in comparison with the control group) in the rest of the monitoring time. Conclusions The first period of NK cell recovery occurs between three and six months after transplantation. Reconstitution is transient and the number of NK cells varies in the first years.Background Medical surgeons specialists are exposed to risk factors, the most frequent being those of the psychosocial type, where burnout syndrome is included due to the type of exposure and diversification of their activities as a member of the health team and the legal and socio-labor repercussions. Objective To determine the prevalence and risk factors of burnout in medical surgeons. Method Observational, descriptive and cross-sectional study in 296 specialists. The data was processed descriptively and inferentially with the support of the SPSS 15.0 and Epi-infoV6.1 program. Results There was a response in 92.5% of the interviewees and the burnout was found in 40.2%. Significant differences were detected in age under 40 years, not having a stable partner, and less then 15 years with your partner, being a medical oncologist, having less then 10 years of professional seniority and in the workplace. Conclusions Burnout is frequent (40.2%), as risk factors are, being woman; under 40 years old; not having a stable partner, under 15 years with her and not working this, without children; surgical medical oncologist; less then 10 years of professional seniority and job position, night shift; definitive hiring; not having another job and more than 4 h in it. The involvement of the subscales behaves like the syndrome. There was a negative correlation with burnout between emotional exhaustion and depersonalization, and positive with lack of personal fulfillment at work.Introduction Duplicity of the common bile duct (BCBD) is an unusual congenital disorder. Case report A 80-year-old woman with duplication of the common bile duct with retrograde endoscopic cholangiopancreatography (ERCP) who did not resolve the symptoms. Discussion Our case is a variant of type IV to the classification of DCBC. The MR cholangiography and presurgical ERCP allows assessment of the bile ducts, their caliber, and assessment of abnormalities. The treatment before DCBC will depend on the clinic and the type of opening of the CBCA. Conclusions It is important to perform a pre-surgical study and during surgery with CIO.Background There is little information of intensive care unit (ICU) performance when it's relocated to a totally new and equipped area. Objective To analyze the clinical performance and use of resources of a new respiratory-ICU (nRICU) in a large third-level care hospital. Method Cross-sectional, comparative study using prospective data of patients admitted from July 17, 2017 to July 17, 2018. The Rapoport adjusted method was used to obtain the standardized clinical performance index (SCPI) and the standardized resource use index (SRUI). Results Out of 354 patients, those who were readmissions or remained hospitalized and those whose treatment was withheld or withdrawn where excluded from the analysis. In 301 patients, the observed survival at hospital discharge was 63% while the expected survival was 67.7%. Values of SCPI and SRUI were -1.03 and 0.05 respectively, placing results in coordinates within two standard deviations when plotted in the Rapoport chart. There was a statistically significant difference in survival when comparing the study period with outcomes obtained in the RICU before its relocation (63% vs. 55%, p = 0.01). Conclusions In its 1st year of operation, the nRICU had better clinical performance compared to the former RICU, with no change in the use of resources.Background In the distribution of the veins, it corresponds in the path and by its affluent to their arterial counterpart.  https://www.selleckchem.com/products/VX-745.html  For the pelvic surgeon faced with pelvic surgical pathology, the knowledge of the distribution of the venous vessels is especially important in view of novel surgical techniques and current approaches. The majority of the reports are on common iliac vein (CIV) or the inferior vena cava. To the best of our knowledge, there are no papers describing posterior extrapelvic affluents that drain into the internal iliac vein (IIV). Objective The aim of this work was to describe the pattern of the constitution of the IIV in 17 dissection specimens taken at our institution. Materials and methods We dissected and registered the anatomic variations of the posterior extrapelvic tributaries to the IIVs. Results Moreover, we describe the presence of a vein here that is, as far as we know, the first report of a vein that is formed from the posterior extrapelvic veins that drain exactly onto the anterior surface of the CIV. We also describe herein the variants that we have found. Conclusions The ignorance of the anatomic variations in the posterior extra-pelvic tributaries to the IIVs (internal iliac veins) can lead to fatal consequences in the patients undergoing pelvic surgery.Background Antibody deficiencies encompass a wide spectrum of pathologies and constitute approximately 50 % of primary immunodeficiencies; with cytometry, it is possible to evaluate the immune status rapidly, effectively and at low cost. Objective To assess, by means of flow cytometry, the cells of patients with three types of primary humoral immunodeficiencies. Method Using flow cytometry, blood samples from patients and healthy subjects were analyzed with different monoclonal antibodies. Results Using various stains, a severe decrease in B lymphocytes was shown in patients with X-linked agammaglobulinemia, as well as a lack of CD154 expression in patients with hyper-immunoglobulin M syndrome, and heterogeneity of B lymphocyte subpopulations in patients with common variable immunodeficiency. Conclusion Flow cytometry enables early diagnosis of primary immunodeficiencies with a high level of confidence and, in many cases, identification of the genes involved.