indings provide valid evidence supporting precision interventions to reduce the extra suicide mortality among Whites by targeting specific age ranges with different suicide methods. Our study aimed to describe body phenotypes (BP) estimated by multivariate analysis and their association with body mass. Body phenotypes were defined based on demographic variables, anthropometric data (body mass, height, skinfolds and circumferences), body composition (phase angle measured by bioelectrical impedance analysis), biochemical parameters (triglycerides, glucose, total cholesterol ratio/Low Density Lipoproteins (LDL), haemoglobin and sexual maturation (pubic hair and breasts or gonads). Analysis of variance (ANOVA) was performed to verify the differences between skin colour and the stages of pubertal development, body phenotypes, body composition, anthropometric, and biochemical variables. Cities of São Paulo-SP, Piracicaba-SP and Florianópolis-SC from Brazil and the United States. 9269 adolescents aged between 10 to 15 years old. The composition of BP was similar in all surveys, which are BP1 was composed by skinfolds, body mass and circumferences variables; BP2 by pubic hair, breast in girls or gonad in boys, height and age; BP3 by cholesterol, triglycerides and glucose; and BP4 by phase angle, haemoglobin and glucose (negative loading). There was a strong correlation (r = 0.9, p <0.001) between BP1 and body mass index. We highlighted independence observed between biochemical parameters, anthropometry, body composition and sexual maturation. BP may support the calculation of scores for diagnosis of obesity based on anthropometric variables and overcome ambiguity in the isolated use of body mass index. We highlighted independence observed between biochemical parameters, anthropometry, body composition and sexual maturation. BP may support the calculation of scores for diagnosis of obesity based on anthropometric variables and overcome ambiguity in the isolated use of body mass index. The current study aimed to predict disability-adjusted life years (DALY) rate in Japan through 2040 with plausible future scenarios of fruit intake for neoplasms, cardiovascular diseases (CVD) and diabetes and kidney diseases (DKD). Data from National Health and Nutrition Surveys and the Global Burden of Diseases study in 2017 were used. We developed an autoregressive integrated moving average model with four future scenarios. Reference scenario maintains the current trend. Best scenario assumes that the goal defined in Health Japan 21 is achieved in 2023 and is kept constant afterwards. Moderate scenario assumes that the goal is achieved in 2040. Constant scenario applies the same proportion of 2016 for the period between 2017 and 2040. DALY rates in Japan were predicted for the period between 2017 and 2040. Population aged more than than 20 years old. In our reference forecast, the DALY rates in all-ages group were projected to be stable for CVD and continue increasing for neoplasms and DKD. Age group-specific DALY rates for these three disease groups were forecasted to decrease, with some exceptions. Among men aged 20-49 years, DALY attributable to CVD differed substantially between the scenarios, implying that there is a significant potential for reducing the burden of CVD by increasing fruit intake at the population level. Our scenario analysis shows that higher fruit intake is associated with lower disease burden in Japan. Further research is required to assess which policies and interventions can be used to achieve an increase in fruit intake as modelled in the scenarios of the current study. Our scenario analysis shows that higher fruit intake is associated with lower disease burden in Japan. Further research is required to assess which policies and interventions can be used to achieve an increase in fruit intake as modelled in the scenarios of the current study. To examine the association between food insecurity (FI) and obesity, measured by BMI and waist circumference (WC), among young adults and test the moderating role of biological sex and the mediating role of diet healthfulness (DH). Cross-sectional. National Health and Nutrition Examination Survey 2011-2016. The sample included 4667 young adults aged 18-35 years. Given the interaction terms between sex and FI, biological sex was a moderator between both FI and WC (P = 0·031) and FI and BMI (P = 0·007) among young adults. FI was associated with a 1·16 kg/m2 higher BMI (95 % CI 0·27, 2·05) and a 2·09 cm larger WC (95 % CI 0·05, 4·14) among young female adults, while FI was associated with a 0·26 kg/m2 higher BMI (95 % CI -0·65, 1·16) and a 0·78 cm larger WC (95 % CI -1·13, 2·89) among young male adults. DH mediated the relationships between both FI and BMI (indirect effect β = 0·14; 95 % CI 0·05, 0·23) and FI and WC (indirect effect β = 0·31; 95 % CI 0·10, 0·51) among females. Females with FI had poorer DH and thus had higher BMI and larger WC. Young female adults with FI were more likely to experience overall and abdominal obesity compared with their male counterparts. Results also suggest that females with FI had poorer DH and thus had increased risk of both abdominal and overall obesity. Young female adults with FI were more likely to experience overall and abdominal obesity compared with their male counterparts. Results also suggest that females with FI had poorer DH and thus had increased risk of both abdominal and overall obesity. Patients with epilepsy are at risk for several lifetime problems, in which neuropsychological impairments may represent an impacting factor. https://www.selleckchem.com/products/snx-2112.html We evaluated the neuropsychological functions in children suffering from three main epilepsy categories. Further, we analyzed the longitudinal evolution of the neuropsychological profile over time. Patients undergoing neuropsychological evaluation at our Department from 2012 to 2018 were identified retrospectively. We selected patients aged 6-16 years and with at least two evaluations. Three epilepsy categories were considered focal/structural, focal self-limited, and idiopathic generalized. Each evaluation included the same structured assessment of main neuropsychological domains. The effect of the epilepsy category, illness duration, seizure status, and medication was computed in multilevel models. We identified 103 patients (focal self-limited = 27; focal/structural = 51; and idiopathic generalized = 25), for 233 evaluations. The majority of deficits were reported in attention and executive functions (>30% of patients); the results were dichotomized to obtain global indexes.