https://www.selleckchem.com/products/apx2009.html This scoping review aims to map studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women. In the United States, two vaccines are recommended for all pregnant women to prevent illness in the infant inactivated influenza vaccine (recommended since 2004) and the combined tetanus-diphtheria-acellular pertussis (Tdap) vaccine (recommended since 2013). Because of the ethical constraints in conducting randomized clinical trials to measure the effects on the infant, there is great interest in using electronic health care data or administrative claims data to study the effects of maternal immunization on the infant's health, and it is anticipated that such studies may be submitted to support regulatory decision-making. This scoping review will map the studies conducted to date that address these questions and provide a context for considering the regulatory issues that may arise in the future. Studies that report on pregnant women receiving immuhesis. To synthesize evidence on the effectiveness of multidisciplinary self-management interventions for glycaemic control in people with type 1 diabetes. Type 1 diabetes is a chronic autoimmune disease. Self-management education led by a multidisciplinary team facilitates those with diabetes to acquire the necessary knowledge and skillset to improve their outcomes and quality of life. This review will consider studies on people aged 16 years and over with type 1 diabetes, investigating the effectiveness of multidisciplinary self-management interventions. The primary outcome of interest is glycemic control as measured by glycated hemoglobin levels. Secondary outcomes include quality of life as measured by validated screening tools and adverse outcomes, such as number of hypoglycemia, hyperglycemia and diabetic ketoacidosis events. This review will consider all quantitative study designs. Studies published in English s