https://www.selleckchem.com/products/atglistatin.html 5% (n=25) and 15.3% (n=10) of the patients, respectively. In multivariate analysis, we found that PSA RR≥ 30% in patients had a statistically significant advantage in terms of PFS ( HR 0.38, 95% CI (0.13-0.71;p=0.03). In conclusion, 30% PSA RR was significantly associated with a better PFS. In conclusion, 30% PSA RR was significantly associated with a better PFS. To explore the associations between the expressions of micro ribonucleic acid (miR)-135 and miR-92a and the pathogenesis of prostate cancer, as well as their clinical significance. A total of 40 prostate cancer patients were studied. The associations of expressions of miR-135 and miR-92a with the pathological Gleason score and expression of prostate specific antigen (PSA) were assessed, the sensitivity and specificity of miR-135 and miR-92a in the diagnosis of prostate cancer were compared, and the associations between the expressions of miR-135 and miR-92a and the prognosis of prostate cancer patients were evaluated. In patients with pathological Gleason score ≥8 points the expression level of miR-135 was significantly lower (p<0.05), while that of miR-92a was significantly higher than those in patients with pathological Gleason score <8 points (p<0.05). In patients with PSA expression >10 ng/mL the expression level of miR-135 was obviously lower (p<0.05), while that of miR-92a was obviopressions of miR-135 and miR-92a are of certain value in screening prostate cancer. The prognosis and survival of patients are positively correlated with the miR-135 expression and negatively correlated with the miR-92a expression. Leukemia causes tremendous human mortality especially in children and young adults. This study was undertaken to investigate the anticancer effects of Solanine against the normal human NCI-H526 and human leukemia AML-193 cell lines. Cell proliferation was determined by MTT assay. DAPI and annexin V/propidium iodide (PI) assays were used for th