https://www.selleckchem.com/products/muramyl-dipeptide.html Medical diagnosis has seen a tremendous advancement in the recent years due to the advent of modern and hybrid techniques that aid in screening and management of the disease. This paper figures a predictive model for detecting neurodegenerative diseases like glaucoma, Parkinson's disease and carcinogenic diseases like breast cancer. The proposed approach focuses on enhancing the efficiency of adaptive neuro-fuzzy inference system (ANFIS) using a modified glowworm swarm optimization algorithm (M-GSO). This algorithm is a global optimization wrapper approach that simulates the collective behavior of glowworms in nature during food search. However, it still suffers from being trapped in local minima. Hence in order to improve glowworm swarm optimization algorithm, differential evolution (DE) algorithm is utilized to enhance the behavior of glowworms. The proposed (DE-GSO-ANFIS) approach estimates suitable prediction parameters of ANFIS by employing DE-GSO algorithm. The outcomes of the proposed model are compared with traditional ANFIS model, genetic algorithm-ANFIS (GA-ANFIS), particle swarm optimization-ANFIS (PSO-ANFIS), lion optimization algorithm-ANFIS (LOA-ANFIS), differential evolution-ANFIS (DE-ANFIS) and glowworm swarm optimization (GSO). Experimental results depict better performance and superiority of the DE-GSO-ANFIS over the similar methods in predicting medical disorders.Along with the COVID-19 outbreak, which has been a global threat for public health, the unconfirmed information about the pandemic in circulation has become another threat. Hence, it has become important to improve public understanding of science with a focus on explaining the nature of uncertainty in science and its impacts. The goal of the present study was to explore pre-service teachers' analysis of claims related to the COVID-19 pandemic throughout an 8-week online implementation of a pre-service teachers' analysis task, foc