https://www.selleckchem.com/products/nvs-stg2.html We discovered that these modifications were related in terms of the degree of sulfation and the α- or β-linkage of HexNY (Y = SO3- or Ac), and especially that the different linkage of the disaccharide unit is the main factor in modification. In addition, the method based on micro-free-radical reaction and HILIC-FTMS is both effective and sensitive, thus suggesting its broad practical value for the structural characterization and in the biological structure-function studies of GAGs. Blending two biodegradable aliphatic polyesters with complementary bulk properties is an easy way of tuning their final properties. In this work, the ductile poly(butylene succinate) was mixed with polylactide, and as expectable, the blends show improved toughness with sharply reduced strengths. The pristine cellulose nanofibers were then used as the reinforcement for the blends. It is found that most nanofibers are dispersed in the polylactide phase because polylactide has better affinity to nanofibers, and the lower viscosity level of polylactide also favors driving nanofibers into the continuous polylactide phase during melting mixing. In this case, the strength and rigidity losses resulted from the presence of soft poly(butylene succinate) phase are compensated to some extent. To further improve mechanical properties, a two-step approach (reactive processing of blends, followed by the incorporation with nanofibers) was developed. This work provides an interesting way of fabricating fully biodegradable composites with well-balanced mechanical performance. A glycosaminoglycan was isolated from the sea cucumber Holothuria coluber (HcFG). A series of oligosaccharide fragments (dp range 3-11) were prepared from its β-eliminative depolymerized product (dHcFG). Extensive NMR characterization of the oligosaccharides indicated the d-GlcA-β1,3-d-GalNAc4S6S repeating disaccharide backbone was substituted by monosaccharide branches comprising of