https://www.selleckchem.com/products/vx-561.html The COVID-19 pandemic has had not only a tremendous impact on public health but also on the care of many pre-COVID-19 diseases, such as stroke. The pandemic has tested the robustness of comprehensive stroke care programs. Especially during the months of confinement, an alarming increase in the incidence of several risk factors for cerebrovascular diseases was noticed, without, however, the proportional strengthening of strategies for the prevention and/or control of comorbidities. Patients who had already suffered a stroke were neglected from the secondary prevention routine and neurological rehabilitation therapies. Regarding the acute treatment, the fear of contagion in the hospital environment promoted a significant delay in the time from the onset of symptoms to admission to an emergency department as well as in the door to imaging and door to needle times. Moreover, the pandemic also exposed the enormous inequalities in the approach to cerebrovascular diseases worldwide. Actually, many consequences of COVID-19 in stroke care will persist for months even after pandemic control. Strategies to combat the pandemic must be reconciled with the fight against stroke in a way that does not exclude any patient from access to the best possible care.This paper presents an approach to access real time data from underground mine. Two advance technologies are presented that can improve the adverse environmental effect of underground mine. Visible light communication (VLC) technology is incorporated to estimate the location of miners inside the mine. The distribution of signal to noise ratio (SNR) for VLC system is also studied. In the second part of the paper, long range (LoRa) technology is introduced for transmitting underground information to above the surface control room. This paper also includes details of the LoRa technology, and presents comparison of ranges with existing above the surface technologies.Human respiratory