Benign myofibroblastic lesions can clinically and histologically be mistaken for sarcoma. Excessive and potentially disfiguring surgical treatment can be avoided by ruling out malignancy. We present the case of a low-grade, myofibroblastic lesion of the lip, which shows how detailed clinical examination rather than reliance on histopathological information alone helped to achieve this. Differential diagnoses of myofibroblastic lesions are also discussed. Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.The atlas (C1) and axis (C2) have distinct morphologies to support the skull and facilitate head rotation and neck flexion. Congenital defects of C1 posterior arch are rare. We present a case of a 59-year-old man with both an absent C1 posterior arch with concomitant os odontoideum. The patient presented with neck crepitus, moderate neck pain and progressive worsening upper limbs paraesthesia and pain. Computed tomography (CT) revealed non-union between the odontoid process and body of axis as well as absence of C1 posterior arch. An occiput C0-C3 fusion was performed. The patient's symptoms improved significantly, and he is functioning well at 12 months. CT showed solid fusion without implant migration. Concomitant os odontoideum with aplastic C1 posterior arch is rare with limited evidence to guide management. Posterior fixation and fusion may be a potential solution to prevent dynamic compression, thereby preventing further myelopathy and related complications. Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.An internal hernia is a protrusion of viscera through a congenital or acquired defect in the mesentery of peritoneum. They account for less then 0.9% of all small bowel obstructions [1] and ~4% of obstructions due to hernias [2]. We present a rare case of closed loop obstruction secondary to a band adhesion traversing the lower abdomen from a sigmoid colon appendage epiploicae to the right pelvic wall. A 82-year-old woman presented to the emergency department with nausea, vomiting and worsening right sided abdominal pain for 24 h, on the background of previous pelvic radiation and hysterectomy for uterine cancer. She was subsequently found to have a closed loop obstruction with 30 cm of ischemic bowel strangulated by a band adhesion from a sigmoid colon appendage epiploicae to the right abdominal wall. The patient underwent a successful small bowel resection with primary anastomosis and made an uneventful recovery. Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.One of the main roadblocks that still hamper the practical use of molecular nanomagnets is their cryogenic working temperature. In the pursuit of rational strategies to design new molecular nanomagnets with increasing blocking temperature, ab initio methodologies play an important role by guiding synthetic efforts at the lab stage. Nevertheless, when evaluating vibration-induced spin relaxation, these methodologies are still far from being computationally fast enough to provide a useful predictive framework. Herein, we present an inexpensive first-principles method devoted to evaluating vibration-induced spin relaxation in molecular f-block single-ion magnets, with the important advantage of requiring only one CASSCF calculation. The method is illustrated using two case studies based on uranium as the magnetic centre. Finally, we propose chemical modifications in the ligand environment with the aim of suppressing spin relaxation. This journal is © The Royal Society of Chemistry 2020.We report the bidirectional enantioselective synthesis of bis-benzofuran atropisomeric oligoarenes featuring two distal C-C stereogenic axes obtained by a two-fold central-to-axial chirality conversion upon oxidative aromatization. The key enantioenriched centrally chiral bis-dihydrobenzofuran precursors were synthesized via a bidirectional diastereo- and enantio-selective organocatalyzed domino reaction between simple achiral and easily accessible dihydroxylated aromatics and chloronitroalkenes.  https://www.selleckchem.com/products/17-AAG(Geldanamycin).html  Moreover, the stereodivergent nature of the methodology was established by synthesizing both diastereomers of a non-symmetrically functionalized bis-axially chiral oligoarene. This journal is © The Royal Society of Chemistry 2020.It is well-recognized that block copolymer self-assembly in solution typically produces spheres, worms or vesicles, with the relative volume fraction of each block dictating the copolymer morphology. Stimulus-responsive diblock copolymers that can undergo either sphere/worm or vesicle/worm transitions are also well-documented. Herein we report a new amphiphilic diblock copolymer that can form spheres, worms, vesicles or lamellae in aqueous solution. Such self-assembly behavior is unprecedented for a single diblock copolymer of fixed composition yet is achieved simply by raising the solution temperature from 1 °C (spheres) to 25 °C (worms) to 50 °C (vesicles) to 70 °C (lamellae). Heating increases the degree of hydration (and hence the effective volume fraction) of the core-forming block, with this parameter being solely responsible for driving the sphere-to-worm, worm-to-vesicle and vesicle-to-lamellae transitions. The first two transitions exhibit excellent reversibility but the vesicle-to-lamellae transition exhibits hysteresis on cooling. This new thermoresponsive diblock copolymer provides a useful model for studying such morphological transitions and is likely to be of significant interest for theoretical studies. This journal is © The Royal Society of Chemistry 2020.The efficient and regioselective electrosynthesis of tetra- and hexa-functionalized [60]fullerene derivatives with unprecedented addition patterns has been achieved. The tetra-functionalized [60]fullerene derivative with an intriguing 1,2,4,17-addition pattern is regioselectively obtained by cyclization reaction of the dianionic species generated electrochemically from a [60]fulleroindoline with 1,2-bis(bromomethyl)benzene at 0 °C, and can be converted to the more stable 1,2,3,4-adduct at 25 °C. Furthermore, the hexa-functionalized [60]fullerene derivative with the 1,2,3,4,9,10-addition pattern displaying a unique "S"-shaped configuration can be synthesized by protonation of the electrochemically generated dianion of the obtained tetra-functionalized 1,2,4,17-adduct. The structures of the tetra- and hexa-functionalized products have been determined by spectroscopic data and single-crystal X-ray analysis. This journal is © The Royal Society of Chemistry 2020.