https://www.selleckchem.com/products/OSI027.html Our results indicated that snowmelt did not alter accumulation of the examined lipophilic contaminants, and no consistent seasonal differences were observed in their accumulation. A spatial pattern was observed for PBDE congeners, where lowest levels were measured in fish tissues from a reference site, and highest concentrations were measured in fish collected downstream of the effluent discharge, indicating that municipal effluent discharge contributes to the elevated PBDE levels in fish residing in this effluent-dominated stream. We further calculated screening level consumption risks following United States Environmental Protection Agency (EPA) methods, and identified the importance of considering discharge gradients in effluent-dominated systems during bioaccumulation assessments.The occurrence of phthalate esters (PAEs) and microplastics (MPs) was simultaneously investigated in four wastewater treatment plants (WWTPs), receiving water bodies and reclaimed water treatment processes (RWTPs) in winter and spring. Four PAEs (dimethyl phthalate, dibutyl phthalate, diisobutyl phthalate, and di(2-ethylhexyl)phthalate) were detected. The total concentrations of PAEs were 568.9-1847.5 ng/L in the four WWTP effluents and 39.9-1847.5 ng/L in the four receiving water bodies. Di(2-ethylhexyl)phthalate had the highest concentration among the PAEs. MPs were mostly in the form of granules and fragments with size less then 0.01 mm in the four WWTP effluents (276-1030 items/L) and receiving water bodies (103-4458 items/L). The four WWTP effluents were important sources of PAEs to the receiving water bodies in spring but were not likely to be the sources of MPs. The overall removal rates of PAEs and MPs were 47.7%-81.6% and 63.5%-95.4% in the four RWTPs. Low or negative removal rates of PAEs were observed in chlorination and ozonation. Clarification, filtration (except ultrafiltration) and reverse osmosis were the dominant processe