https://www.selleckchem.com/products/spautin-1.html Furthermore, the EQ-5D index and the EQ-5D VAS score were calculated and HbA1c levels were assessed. The change in the EQ-5D-5L index score (post-pre) was 0.01 in the control group and 0.04 in the intervention group (  = 0.041). The change in the VAS score was -0.07in the control group (post-pre) and 2.66 in the intervention group (  = 0.000). Pharmacist counseling may help improve the HRQoL of Prolanis T2DM patients. Pharmacist counseling may help improve the HRQoL of Prolanis T2DM patients. The purpose of this study was to investigate the effects of interval training on cardio metabolic risk factors and nitric oxide in type 2 diabetes patients. This single blinded randomized controlled trial was conducted at cardiology clinic of Rajaee hospital in Karaj. Thirty female patients with type 2 diabetes randomly assigned to interval training exercise (  = 15) and control (  = 15). In interval training exercise patients received interval training exercise with 18 sessions (three sessions per week). Each training session took 25min and consists a single set of exercise with 10 time repetitions. Training was performed on a cycle ergometer set in constant watt mode at a pedal cadence of 80-100 revolutions/min. Each repetition of the training takes 60s and there will be a 60s recovery pried between each repetition. Each training session include a 3-min warm-up and 2-min cool-down at 50W for a total of 25min. Blood samples and of all the subjects were taken at baseline, 3weeks after intervention and at the end of the study (6weeks). In intervention group, comparing with controls participants, a significant decrease were observed in levels of total cholesterol, triglyceride and HA1c after training program (  < 0.05). Moreover,exercise significantly increased the level of NOx (  < 0.05). Other cardiometabolic risk factors including SBP, DBP, FPG, LDL, HDL, insulin level, insulin resistance, HR, VO2 max, did not show significan