https://www.selleckchem.com/products/blasticidin-s-hcl.html To describe epidemiological and clinical features of patients confirmed as having SARS-CoV-2 infection and managed in isolation at home. We performed a multicenter retrospective study enrolling all SARS-CoV-2-positive adults evaluated from 28 February to 31 May 2020 at one of nine COVID-19 Units in southern Italy we included patients receiving care at home and those admitted to hospital. We defined patients with not-severe disease if they were asymptomatic or experienced a mild infection that did not need oxygen (O2) therapy and those with a severe infection if hospitalized and required O2 therapy. We enrolled 415 patients with SARS-CoV-2 infection 77 were managed in isolation at home, 338 required hospital management. The 77 patients in home isolation were less frequently male than hospitalized patients (55% vs. 64%; less then 0.01) and were younger (median age 45 years (IQR19) vs. 62 (IQR 22); p less then 0.01), had a lower Charlson comorbidity index (median 0 (IQR2) vs. 6 (IQR 3); p less then 0.01), and included fewer subjects with an underlying chronic disease (36% vs. 59%; p less then 0.01). According to a binomial logistic regression analysis, a younger age (OR 0.96 (95% IC 0.94-0.98), p less then 0.01) and a low Charlson comorbidity index (OR 0.66 (95% IC 0.54-0.83); p less then 0.01) were independent factors associated with at-home management. The identification of subjects with SARS-CoV-2 infection who could be managed in home isolation is useful in clinical practice. A younger age and no comorbidities were identified as factors independently associated with home management.The influence of dispersing Al-metal complex on the optical properties of PVA was investigated using UV-visible spectroscopy. Polymer composite films with various Al3+-complex amounts in the PVA matrix were arranged by solution casting technique by means of distilled water as a widespread solvent. The formation of Al3+-metal com