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https://www.selleckchem.com/products/sn-38.html The pathogen of viral hemorrhagic fever (VHF), which is harmful to human health, is a hemorrhagic fever virus. Clinicians have long needed convenient and sensitive point-of-care rapid diagnostic tests (RDTs) for hemorrhagic fever viruses. Commonly used methods for pathogen detection rely on conventional culture-based tests, antibody-based assays and polymerase chain reaction (PCR)-based techniques. However, these methods are costly, laborious and time-consuming. Herein, we present a simple and sensitive biosensor for the rapid detection of hemorrhagic fever viruses. For this assay, we develop lateral flow biosensors (LFBs) based on magnetic beads and nicking enzyme-assisted isothermal strand-displacement amplification (SDA) for the detection of hemorrhagic fever viruses. The detection limit of this assay is 10 fM.1,4-Bis(trimethysilyl)-1,4-dihydropyrazine 1 has been utilized as a small molecule precursor for carbonization to N,O-containing few-layered carbon sheets 3via the formation of a polymeric material 2 upon simple air exposure at room temperature. Without any further purification, this multi-functionalized carbon material 3 exhibited excellent anode performance in a lithium ion battery.Localised singlet diradicals are key intermediates in bond homolysis, which plays a crucial role in chemical reactions. However, thorough experimental analyses of the reaction dynamics and chemical properties are generally difficult because bond formation is rapid, even under low-temperature matrix conditions. In this study, the effects of solvent and pressure on the lifetimes of long-lived singlet diradicals with bulky substituents were investigated. The solvent dynamic effect was revealed to provide control over the rate constant of radical-radical coupling reactions, and an almost bottleable singlet diradical with a lifetime of ∼2 s at 293 K was obtained. Anti-type I interferon (IFN) autoantibodies have been reported in patient

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