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https://www.selleckchem.com/ We aimed to report the pathological features of T lymphocytes in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy (GFAP-A). A retrospective pathological analysis of patients with GFAP-A was performed. Eight patients with GFAP-immunoglobulin G (IgG) and pathological data were included. Their biopsy findings were similar, and all showed marked lymphocytic infiltration in the white matter, with perivascular predominance. The lymphocytic infiltration was predominantly composed of CD8 T lymphocytes rather than CD4 T lymphocytes, except in one patient who had overlapping positive myelin oligodendrocyte glycoprotein-IgG. Unlike CD4 T cells, CD8 T cells were frequently observed adjacent to dystrophic neurons and astrocytes. There was also diffuse infiltration by CD68 and CD163 macrophages. CD8 astrocytes were identified in two samples, but no CD4 astrocytes were observed. A predominance of CD8 T cells may be an important pathological and diagnostic feature in GFAP-A. A predominance of CD8+ T cells may be an important pathological and diagnostic feature in GFAP-A.Increasing awareness of inefficient meat production and its future impact on global food security has led the food industry to look for a sustainable approach. Meat products have superior sensorial perception, because of their molecular composition and fibrous structure. Current understanding in the science of food structuring has enabled the utilization of alternative or nonmeat protein ingredients to create novel structured matrices that could resemble the textural functionality of real meat. The physicochemical and structural changes that occur in concentrated protein systems during thermomechanical processing lead to the creation of a fibrous or layered meat-like texture. Phase transitions in concentrated protein systems during protein-protein, protein-polysaccharide, protein-lipid, and protein-water interactions significantly influence the texture and the overall sen

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